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You should consult your doctor also if you are taking any medication to treat lung complications, such as bronchodilators, e.g. ipratropium (Atrovent) or tiotropium (Spiriva). You should avoid combing Vicodin with any treatments for irritable bowel sydrome also. The best approach is to avoid mixing any medications with Vicodin unless it is absolutely necessary. Seek medical advice before you take any herbal supplements, minerals, vitamins, cold and flu treatments, allergy treatments, or any other over-the-counter medicine. Always check to see how much acetaminophen is contained within each tablet, and make sure that no more than 4 grams of it is ingested per day.